Key words: Moraxella (Branhamella) catarrhalis, drug resistance, respiratory tract infections, virulence MORAXELLA CATARRHALIS – PATOGEN GÓRNYCH DRÓG ODDECHOWYCH 69 W 1984 roku na podstawie pokrewieństwa genetycz-

Bengtsson-Palme J, Kristiansson E, Larsson DGJ, Environmental factors Moore ERB, Draft Genome Sequence of Moraxella catarrhalis Type Strain CCUG 353T, Spectrometry Shotgun Proteomic Characterization and Typing of Pathogenic

These include irritation to the eyes by ultra-violet light (in sunlight), dust, long vegetation and flies. The incidence of the disease is highest in the summer months. The ability of M. catarrhalis to resist complement-mediated lysis is considered to be an important virulence factor of this organism [ 17, 18 ]. Similar to the case in Neisseria species, complement resistance of M. catarrhalis is likely to be multifactorial, but the molecular basis is only partially understood. Recently, we showed that complement resistance is an important virulence factor of Moraxella (Branhamella) catarrhalis. Our study used a serum bactericidal assay to determine complement resistance Complement resistance is a virulence factor of Branhamella (Moraxella) catarrhalis.

Influensa - as a Negative Pathogenic Agents Haemophilus influenzae : Barnstable County . MeSH terms. Animals. Bacterial Proteins / genetics. Bacterial Proteins / immunology. Bacterial Vaccines / immunology. Humans.

Moraxella catarrhalis (formerly known as Branhamella catarrhalis) has emerged as a significant bacterial pathogen of humans over the past two decades. During this period, microbiological and molecular diagnostic techniques have been developed and improved for M. catarrhalis, allowing the adequate determination and taxonomic positioning of this pathogen.

MeSH terms. Animals. Bacterial Proteins / genetics.

Perez Vidakovics, Laura and Kristian Riesbeck. "Virulence mechanisms of Moraxella in the pathogenesis of infection.". Current Opinion in Infectious Diseases. 2009, 22(3). 279-285.

Currently known virulence factors include OMPs, LOS, and metabolic pathways, which are involved in adhesion, invasion, biofilm formation, modulation of the host immune system, and acquisition of nutrients. For reference, the major virulence factors currently known to be associated with M. catarrhalis pathogenesis are summarized in Table 1. Moraxella catarrhalis is a common human respiratory tract pathogen. Its virulence factors associated with whole bacteria or outer membrane vesicles (OMVs) aid infection, colonization and may induce Of note, genes for almost all of the established virulence factors (described in the following Structure and Virulence Mechanisms section) are encoded in the core genome of M. catarrhalis. Therefore, the core genome is an important platform for identifying potential vaccine antigens and for designing anti- M. catarrhalis antimicrobial drugs Genomic and Metabolic Studies 1687 Virulence Factors 1690 Immune Response and Vaccine Development 1693 Conclusion 1693 References 1693 In the late 1960s, reports of the isolation of N. catarrhalis as a pathogen re- emerged (Coffey et al., 1967; Feign et al., 1969) and these continued to increase during the 1970s. M. catarrhalis, earlier called Branhamella catarrhalis, is a smart pathogen, gaining significance as a pathogen over few decades, and having an array of virulence factors, of which biofilm formation and lipase and serum or complement resistance are important.12,13 This bacterium is an exclusively human pathogen causing Lower Comparison of Moraxella catarrhalis isolates from children and adults for growth on modified New York City medium and potential virulence factors.

Hu, W. G. av V Schaar · 2013 — and virulence factors specific for the pathogen, and are involved in pathogenesis and bacterial survival. Moraxella catarrhalis and Haemophilus influenzae are [PDF] B cell activation by outer membrane vesicles--a novel virulence mechanism.
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Branhamella catarrhalis virulence factors

The purpose of this study was to investigate complement resistance in Branhamella (Moraxella) catarrhalis isolated from healthy schoolchildren or 6 Sep 2012 catarrhalis-related infection. Interestingly, M. catarrhalis outer membrane vesicles (OMVs) containing mainly UspAs and other virulence factors 26 Jan 2011 Moraxella catarrhalis are pathogenic, gram-negative diplococci that nity factor complex first described in the M. catarrhalis plasmid Catlin BW: Branhamella catarrhalis: an organism gaining respect as a · pa 4 Mar 1996 of Strains of Moraxella catarrhalis Isolated from the Elderly. S. Susan Resistance to complement is an important virulence factor in Catlin BW: Branhamella catarrhalis: An organism gaining respect as a pathogen. 10 Apr 2011 Branhamella catarrhalis,. Moraxella.

New!!: Moraxella catarrhalis and Virulence factor · See more » Virulence-related outer membrane protein family 1995-06-01 · In young children (age 4-5 years), the proportion of complement-resistant strains was around 50%.
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Virulence factors As an important repiratory pathogen, M.(B). catarrhalis is armed with numerous virulence factors to allow its invasion and colonization of human respiratory tract. Several of these factors have been identified and characterized in the last decade including

Eighty percent of isolates from the infected group as opposed to 5% of M. catarrhalis (formally known as Branhamella catarrhalis) has undergone several name changes in the past 100 years [19-20]. It was first described at the end of the nineteenth century when it was named Micrococcus catarrhalis, and it was later changed to Neisseria catarrhalis because of its similarity in phenotype and ecological niche to 2000-04-01 Virulence factor. Virulence factors are molecules produced by bacteria, viruses, fungi, and protozoa that add to their effectiveness and enable them to achieve the following. New!!: Moraxella catarrhalis and Virulence factor · See more » Virulence-related outer membrane protein family 1995-06-01 · In young children (age 4-5 years), the proportion of complement-resistant strains was around 50%. Complement resistance in B. catarrhalis is associated with illness and may hence be considered a virulence factor.